Anti-fibrillarin autoantibodies are useful for the diagnosis and prognosis of systemic sclerosis (SSc).Anti-fibrillarin produces a clumpy nucleolar pattern in indirect immunofluorescence assay on HEp-2 cells (HEp-2 IFA).Here we develop and validate a reliable cell-based anti-fibrillarin assay (Fibrillarin/CBA) for use in clinical diagnostic laborat
Single-cell RNA sequencing (scRNA-seq) is crucial Samsung RZ32M7120WW Free Standing 315 Litres A+ Upright Freezer White for demystifying the cell heterogeneity and differentiation processes, enabling the identification of distinct cell subtypes within a population.However, most of the existing approaches are feeble to comprehensively investigate th
The paper examines a complex of figurative meanings of the entomonym “abelha” (“bee”), manifested in the space of the Portuguese poetic text of the 19th–20th centuries.The purpose of the work is to trace the transformation of the image and its semantic increments.We used methods of contextual, stylistic, Toaster semant
Rasa Shastra is an exclusive branch of ayurveda that uses processed metals and minerals in various combinations.Though the formulations are time tested, safety and quality concerns are being raised since the past two decades.In view of this, it becomes mandatory to generate quality control profiles of such formulations by following available parame
Target location is the basic application of a multistatic sonar system.Determining the position/velocity vector of a target from the related sonar observations is a nonlinear estimation problem.The presence Holders of possible sensor position uncertainties turns this problem into a more challenging hybrid parameter estimation problem.Conventional g